Screening Compounds
InsightTM Discovery Libraries
Librarion’s InsightTM programme is developing screening libraries
that are an extension of the concept of priveliged structures.1
New chemical space, same biological space
Lead-like to drug-like
Can be tailored to target-classes and biological themes
Meet extended Lipinski criteria
No toxicophores
1.“…scaffolds with versatile binding properties such that a single scaffold is able to provide potent and selective ligands for a range
of different biological targets through modification of functional groups…(and)… typically exhibit good drug-like properties…”
De Simone et al, Privileged structures: applications for drug discovery. Comb Chem High Throughput Screen, 2004, 5, 473-494.
Target-directed Libraries
Librarion offers a series of small libraries designed against
kinases and ion channel targets. We can also provide a
selected small molecule set from these libraries containing
approximately 3000 compounds.
SD file data is available for all stock template members
together with virtual libraries containing expanded monomer
series.
For more details click the boxes to the right and/or email us
Building Blocks as Screening Compounds
Some of Librarion’s building blocks may also be suitable for
screening - to see these structures click here.
Special pricing is available for smaller amounts of these compounds
- please email us at info@librarion.com for more details.
Click below for more details
on Target-directed Libraries :
